Drudge Retort: The Other Side of the News
Friday, February 14, 2020

When it comes to viruses, ones from bats are weirdly deadly -- at least to humans.

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Bats may save the Earth from mass extinction. Go bats. Chiroptae 1,---- sapiens 0, go chiroptae.

#1 | Posted by Effeteposer at 2020-02-14 01:49 PM | Reply

What's with this filter software? ---- sapiens is Latin for thinking human,---- is our genus in the order of primates. What a stupid program. Too politically correct by far!!

#2 | Posted by Effeteposer at 2020-02-14 04:06 PM | Reply | Funny: 1

What's with this filter software? ---- sapiens is Latin for thinking human,---- is our genus in the order of primates. What a stupid program. Too politically correct by far!!

#2 | POSTED BY EFFETEPOSER

"----!" *chortles uncontrollably*

#3 | Posted by JeffJ at 2020-02-14 04:13 PM | Reply

"---- Sapiens" the elite of the species...

"---- Sap"... the rest of us...

#4 | Posted by Pegasus at 2020-02-15 08:16 AM | Reply

"----" some of us....

#5 | Posted by Pegasus at 2020-02-15 08:17 AM | Reply

Bats have been around for about 40 million years. They reside in caves and dark places because the sun burns their skin. Clustered in tight groups for warmth, they have to have an extremely effective immune response. Natural selection works, however we should remember that different diseases effect different species differently. We got TB from cattle, deadly to humans, not to the bovine. Rabies doesn't effect bats at all, cattle get an acute form of arthritis from that disease. It kills humans within a couple of weeks.
If we were smart, it might be wise to investigate why bats have immunity or tolerance to so many pathogens. One species we are investigating is crocodiles. The have been around for 400 million years, and they do not get infections, even tho they live in fetid environments. Researchers believe that a whole new field of antibiotics might come from this work.

#6 | Posted by docnjo at 2020-02-15 09:00 AM | Reply | Newsworthy 2

If we were smart, it might be wise to investigate why bats have immunity or tolerance to so many pathogens.

There's multiple labs doing exactly this.

One of the first genes expressed after infection is an antiviral molecule called interferon. There are multiple types (alpha, beta, gamma ect) as well as multiple versions of some of them (humans have 11 copies of interferon alpha IIRC). The role of interferons is to signal to surrounding cells as well as itself that it's infected and to induce a large gene program called interferon stimulated genes that suppress infections.

We know that bat cells have a very different interferon response when infected and trying to figure out why they respond differently as well as the ways they're different is an area of active research.

#7 | Posted by jpw at 2020-02-15 10:57 AM | Reply

#7 | Posted by jpw I think the research into crocodiles is more promising. A bat has a metabolism about 7 times ours. They literally consume their body weight every day. Crocks on the other hand have a metabolism about a half or less than any mammal. What ever mechanisms work to prevent infections in them must be very powerful, as their blood moves very slowly compared to humans.

#8 | Posted by docnjo at 2020-02-15 11:49 AM | Reply

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