What say you about the articles FSU linked to that talk about mass vaccinations leading to more variants and eventually to super variants that will be resistant to all vaccines?:
What do I say?
Vaccines can be incredibly effective, and we've even stamped out some viruses completely.
Super variants? 1918 flu. There was no vaccine, and we got one killer influenza virus. In fact this SARS-CoV-2 didn't come about as the result of vaccinations. Swine flue mutated via an animal host for decades before breaking out.
Also, bacteria are not viruses.
The way we conquered bacterial infections is through hygiene, cleanliness, prophylactics, antibiotics, etc. but bacteria are ubiquitous. Bacteria reproduce on their own.
For a virus to survive it needs a host. It can't reproduce without one. That's why the R0 number is critical. If the R0 drops below 1 the virus burns itself out. It may go into an animal host for years or decades, and reemerge, but they just don't function the say bacteria do.
This doesn't mean that the mutations in the virus won't develop that allow the virus to infect a vaccinated host, especially if we don't have a concerted effort like we do with other viral diseases. That is always a possibility.
But the Alpha and Delta variants didn't arise out of vaccinated populations. So far there's no evidence to support the conjecture at this point.
If the SARS-CoV-2 ends up acting more like an influenza virus then we will be living with this for a long time and with perhaps annual reformulations of the vaccine. That is one possible direction.
My 2 cents.