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... Why it matters: DeSantis will be termed out as governor in 2026, and a seat in the U.S. Senate could provide him the continued relevance he needs to make another campaign for the White House.

How it works: With Rubio's term set to end in 2028, a resignation would grant DeSantis the power to appoint a successor -- one who would serve until a special election in 2026 to determine who finishes the term.

The intrigue: DeSantis could appoint one of his allies to serve as a caretaker, allowing him to run for the seat without an incumbent challenger. His pick would have to be someone credible -- but not a threat.

Potential choices include ...