Neuroscientists at Stanford have linked Alzheimer's disease to the disruption of brain metabolism via the kynurenine pathway, which is affected by amyloid plaque and tau proteins.
Their research has demonstrated that drugs blocking this pathway can restore cognitive function in Alzheimer's mice by improving brain metabolism.
This discovery not only bridges the gap between neuroscience and oncology but also provides a fast track to repurposing existing drugs for Alzheimer's treatment.
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