A Mutation Could Bring Bird Flu Closer to a New Pandemic

@#2 ... "New Pandemic"?

And look see who we've got to protect us after 01/20/25. ...

Yeah, that was (is) my concern also.

And a reason why I was initially reluctant to post this thread.

So far, the possible outcome in the article is just that, as the article states -- a possible outcome.

At this point, I am quite happy it is being monitored by government medical professionals.

fwiw, here's the original (and, if i may add, apparently not yet peer-reviewed) research article...

A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors
www.science.org

...
Editor's summary
In 2021, a highly pathogenic influenza H5N1 clade 2.3.4.4b virus was detected in North America that is capable of infecting a diversity of avian species, marine mammals, and humans. In 2024, clade 2.3.4.4b virus spread widely in dairy cattle in the US, causing a few mild human cases, but retaining specificity for avian receptors.

Historically, this virus has caused up to 30% fatality in humans, so Lin et al. performed a genetic and structural analysis of the mutations necessary to fully switch host receptor recognition.

A single glutamine to leucine mutation at residue 226 of the virus hemagglutinin was sufficient to enact the change from avian to human specificity.

In nature, the occurrence of this single mutation could be an indicator of human pandemic risk. "Caroline Ash
...

With muskhole and brain worm running the nation this should work out well.

Hey magoofs, better stock up on fish tank cleaner and horse paste.

I'm kind of surprised they were allowed to do this kind of research out of biosecurity concerns.

Similar studies were met with an uproar in the early 2010s and a moratorium on gain of function work in respiratory viruses was the result.

Granted, those were in live viruses used in animal models, but the overarching concern then of 'providing a roadmap for bioterrorists' is the same, even with this group's in vitro methods.

Regardless, this shows how little is really required for a serious event to kick off.

A few hundred thousand MAGA need to write out their wills.

#2 | Posted by Zed

Potentially more than that. So far, this isn't showing the 35% case fatality rates avian H5N1 has shown over the past few decades of sporadic cases.

But even at 10%, you'd have lethality rates 10x that of COVID.

The only saving grace is that we already have FDA approved vaxx platforms in existence and likely some stocks of vaccines already produced. I'm sure an updated mRNA will be made available as well (potentially, I guess, depending on Kennedy) so it won't take nearly as long to start vaxxing the population as it did with COVID.

But even 3-5 months could lead to devastating effects on communities if people don't take it seriously.

and, if i may add, apparently not yet peer-reviewed

It's peer reviewed. It's an early version that will likely see corrections prior to full release, but it's peer reviewed.

A word to MAGA: If you don't want bird flu don't f*** chickens.

Stocking up on the TP this weekend... lol

With the amount of illness that has been going around animal farms in general - like herds of Cows full of it, dead cats, sick workers at the same time... It is only a matter of time before this new lab accident spreads like wildfire through people.

Honestly I am in week 7 of an illness - turned the corner about a week ago finally. I didn't test positive for COVID multiple times. Didn't test positive for "the flu" either. Maybe I should have been tested for avian flu. Frankly I got ill after cleaning an area full of bird mess.

@#9

Thanks for the correction.

"But even 3-5 months could lead to devastating effects on communities if people don't take it seriously."

We know with certainty that people won't take it seriously.

Sounds like another plandemic.

~ MAGA dumfux ~

Hmmmm.. I wonder how Trump is going to get those egg prices down.

I wonder how Trump is going to get those egg prices down.

He will say, "We have reduced the cost of eggs on Day One!", and 34% of the population will believe it. Empty G will propose a medal for the achievement.

Experts Warn of Bird Flu Pandemic as Signals of Mutation Mount
www.sciencealert.com

... Health experts have been sounding the alarm about the potential pandemic threat posed by bird flu, which has been showing signs of mutating as it spreads among cows and infects people in the United States.

There is no guarantee that bird flu will ever begin transmitting between humans, and US health authorities have emphasised that the risk to the general public remains low.

The deadly bird flu variant H5N1 first emerged in China in 1996, but over the last four years it has spread more widely than ever before, reaching previously untouched regions such as penguin-haven Antarctica.

More than 300 million poultry birds have been killed or culled since October 2021, while 315 different species of wild birds have died across 79 countries, the World Organisation for Animal Health told AFP.
h5n1 virus particles

Mammals that ate the infected birds, such as seals, have also experienced mass-die offs.

The situation changed again in March, when the virus began spreading among dairy cows across the United States in another first.

Fifty-eight people have tested positive for bird flu in the US this year, including two who had no known exposure to infected animals, according to the Centers for Disease Control and Prevention.

There are also fears that some human cases are going undetected. Researchers said last month that eight out of 115 dairy workers tested in Michigan and Colorado had antibodies for bird flu, suggesting an infection rate of seven percent. ...

Fat Smelvis has his best doctor on the case.

www.nationalmemo.com

Hmmmm.. I wonder how Trump is going to get those egg prices down.
#16 | POSTED BY WHATSLEFT

Slap a tariff on chicken eggs right after the chickens get finished building the coops.

He will say, "We have reduced the cost of eggs on Day One!", and 34% of the population will believe it. Empty G will propose a medal for the achievement.
#17 | POSTED BY REDIAL

I would have flagged this funny if it weren't so damn spot on.

At least the current lying Democrat cabal and Biden and "misinformation" experts will be purged shortly. Sometimes change itself leads to perfection especially in politics.

"You have 15 people, and the 15 within a couple of days is going to be down to close to zero."

~ Robson's favorite rapist ~

Is it just me, or do Robson's posts seem to be getting even more irrelevant and generic as time goes on?

#22 | Posted by Robson

You really are too stupid to live.

But I won't stand in the way of your unnecessary, nasty death by way of some gruesome (but entirely preventable) disease.

If you need to resort to demonizing people that think differently than you it speaks volumes about your mental state. DUMBASS

Stranglers - Skin Deep (1984)
www.youtube.com

Lyrics excerpt...

genius.com

...
Many people tell you that they're your friend
You believe them, you need them for what's round the river bend
Make sure that you're receiving the signals they send
'Cos brother, you've only got two hands to lend

Maybe there's someone who makes you weep
And some nights loom up ahead when you're asleep
Some days there's things on your mind you should keep
Sometimes, it's tougher to look than to leap

Better watch out for the skin deep
Better watch out for the skin deep
(Better watch out) Watch out for the skin deep
(Better watch out) Watch out for the skin deep
Better watch out for the skin deep

One day the track that you're climbing gets steep
Your emotions are frayed, and your nerves are starting to creep
Just remember the days as long as the time that you keep
Brother, you better watch out for the skin deep
...