Thursday, February 20, 2025

Cause of Alzheimer's Might Be Coming From Inside Your Mouth

In recent years, a growing number of scientific studies have backed an alarming hypothesis: Alzheimer's disease isn't just a disease, it's an infection.

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More from the article ...

... While the exact mechanisms of this infection are something researchers are still trying to isolate, numerous studies suggest the deadly spread of Alzheimer's goes way beyond what we used to think.

One such study, published in 2019, suggested what could be one of the most definitive leads yet for a bacterial culprit behind Alzheimer's, and it comes from a somewhat unexpected quarter: gum disease.

In a paper led by senior author Jan Potempa, a microbiologist from the University of Louisville, researchers reported the discovery of Porphyromonas gingivalis -- the pathogen behind chronic periodontitis (aka gum disease) -- in the brains of deceased Alzheimer's patients.

It wasn't the first time the two factors have been linked, but the researchers went further.

In separate experiments with mice, oral infection with the pathogen led to brain colonization by the bacteria, together with increased production of amyloid beta (A), the sticky proteins commonly associated with Alzheimer's. ...


#1 | Posted by LampLighter at 2025-02-20 11:49 PM

Also, for years in Europe, Alzheimer's is often known as Diabetes type 3.

The brain is a place we will never understand.

My wife is a few years into early-onset Alzheimer's. Began in her late 50s. She's now 71. I'm her caregiver. We went through it with her mother too. It's an amazing process to watch. And even the top docs know what happens, but never really why.

#2 | Posted by Dbt2 at 2025-02-22 07:33 AM

"It's an amazing process to watch."

There is a road, no simple highway
Between the dawn and the dark of night
And if you go, no one may follow
That path is for your steps alone

Ripple in still water
When there is no pebble tossed
Nor wind to blow

You who choose to lead must follow
But if you fall you fall alone
If you should stand then who's to guide you?
If I knew the way I would take you home

#3 | Posted by Doc_Sarvis at 2025-02-22 07:42 AM

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