Could the Southwest vote to be Spanish speaking and independent from Mexico or the US? If enough voters there wanted to? Why Not? It happens in other countries.
Slovakia left Czechoslovakia without bloodshed. Yugoslavia became a Charnel House of Internecine War.
Ukraine is not the US. Europe is not America. The world has different traditions.
One size does not fit all.
The Donbass Oblasts wanted to leave Ukraine. The Central Government in Kiev wasn't Down with It.
Civil War. Then Russia seeing an opportunity to Meddle, got involved.
Then NATO got involved. See where this is going?
If everyone had just let the Breakaway Oblasts create their own Republics..like the Czech Republic did with the Slovaks there would have been No War.
But "Superpowers" just can't resist Meddling. It's their prime reason for existing.
The Czech Republic was not Meddled with because the West didn't want anything there.
Russia didn't meddle because the Slovaks aren't Russians and never were.
Yugoslavia was massively meddled with by NATO on bogus humanitarian grounds for access to the region, but primarily because Russia was too Weak at the time to do anything about it.
Maybe isolation isn't that bad of a Choice. Wrap our Oceans ourselves and mind our own business for a while.
It will certainly get fewer people killed around the world.
Even if it doesn't, it won't be Our responsibility or fault for what Others choose to do.
Russia is as Imperialistic as the US. But it's more Regional than Global in scale.
Spheres of Influence are the best hope humanity has for peace and not death by Suicide.
It worked for centuries until the collapse of the Soviet Union gave the West an unrealistic belief that the world belonged to them Alone.