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Monday, March 04, 2024

More frequent use of cannabis was associated with higher odds of adverse cardiovascular outcomes, finds a new study in the Journal of the American Heart Association.

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Study Background: We examined the association between cannabis use and cardiovascular outcomes among the general population, among never-tobacco smokers, and among younger individuals.

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Research Highlights:

An analysis of survey data for 430,000 adults in the U.S. found that using cannabis has a significant association with an increased risk of heart attack and stroke, independent of tobacco use, with higher odds among the adults with more frequent use (more days of use per month). The most common method of cannabis use was smoking, followed by eating or vaporizing it.

The increase in the combined risk of coronary heart disease, heart attack, and stroke was similar to the risk among the subset of adults who had never used e-cigarettes but did use cannabis.

The analyses of found:

Any cannabis use (smoked, eaten or vaporized) was independently associated with a higher number of adverse cardiovascular outcomes (coronary heart disease, myocardial infarction and stroke) and with more frequent use (more days per month), the odds of adverse outcomes were even higher.

The results were similar after controlling for other cardiovascular risk factors, including tobacco and/or e-cigarette use, alcohol consumption, body mass index, Type 2 diabetes and physical activity.

Both daily and non-daily cannabis users had an increased risk of heart attack compared to non-users; daily cannabis users had 25% higher odds of heart attack compared to non-users.

The odds of stroke for daily cannabis users were 42% higher compared to non-users, with lower risk among those who used cannabis less than daily.

more at the thread link

#1 | Posted by Corky at 2024-03-03 07:44 PM | Reply

500 deaths/day?????

#2 | Posted by fresno500 at 2024-03-03 08:39 PM | Reply

This does not surprise me at all.

#3 | Posted by Effeteposer at 2024-03-03 09:22 PM | Reply

The dumb part are the people who think it has no health implications. What they are and to what degree are still being studied, like this one. But anything you put in your body causes negative impacts. You can eat too much broccoli. You can drink too much water. Our bodies are dying after a certain age (and it's not old age) and anything you consume increases that effect. I have to stop my daily habit soon, I know that, but at least some states are giving people the option and not blocking our freedoms.

#4 | Posted by humtake at 2024-03-04 11:44 AM | Reply

I miss Nullifidian. He was very interested in this issue and could debate the virtues of MJ use with anybody here.

#5 | Posted by eberly at 2024-03-04 11:46 AM | Reply | Newsworthy 2

He was very interested in this issue and could debate the virtues of MJ use with anybody here.

#5 | POSTED BY EBERLY

And then he died. Do you know how? Was it a heart attack or a stroke?

And what did you conclude from that?

The article had the usual (for cannabis) flaws. Because cannabis is classified as a schedule 1 drug it has been very difficult if not impossible for any major studies. Most evidence appears to be antidotal.

FTA: The study had several limitations, including that cardiovascular conditions and cannabis use were self-reported, making them potentially subject to recall bias (potential errors in memory); that the authors did not have health data measuring participants' baseline lipid profile or blood pressure; and the study captured data for only a single point in time for the participants.

So basically we are in the same place we were before this study.

We need more studies.

FTA: The authors note that there is a need for prospective cohort studies " studies that follow groups of individuals over time " to examine the association of cannabis use and cardiovascular outcomes while accounting for frequency of cannabis use.

I was gonna do some more studies myself.

Then I got high.


#6 | Posted by donnerboy at 2024-03-04 11:56 AM | Reply | Newsworthy 1

500 deaths/day?????

#2 | POSTED BY FRESNO500

Not even close. Depending on how you measure 1 death per year from toxicity or 350 per year for just detections of it in your blood (but not the direct cause).

From 1998 to 2011, on average 7% of all cases reported to NPSAD had a cannabinoid detected (n = 110 deaths per year), rising to 18% in 2020 (n = 350). Death following cannabis use alone was rare (4% of cases, n = 136/3455). Traumatic injury was the prevalent underlying cause in these cases (62%, n = 84/136), with cannabis toxicity cited in a single case.

pubmed.ncbi.nlm.nih.gov).

#7 | Posted by donnerboy at 2024-03-04 12:02 PM | Reply | Newsworthy 1

So here's what I get from this survey; if only we would have incarcerated more pot smokers they would now be living happy lives today. America needs to wake up and say "Thank you Nancy Reagan." Ron ReaganJr. would disagree but, hey, what does he know?

#8 | Posted by danni at 2024-03-04 12:03 PM | Reply | Funny: 1 | Newsworthy 1

"And then he died. Do you know how? Was it a heart attack or a stroke?
And what did you conclude from that?"

no clue on how he died. I just enjoyed the debate....but I never participated. I know zero about cannibas/MJ, etc.

#9 | Posted by eberly at 2024-03-04 12:11 PM | Reply

Depending on how you measure 1 death per year from toxicity or 350 per year for just detections of it in your blood (but not the direct cause).
#7 | POSTED BY DONNERBOY

Kind missing the point.

"cannabis has a significant association with an increased risk of heart attack and stroke"

#10 | Posted by oneironaut at 2024-03-04 12:24 PM | Reply | Funny: 1

Only 7% consumed? So it is a study of 30,100 people. Vaporized can mean concentrates or dry flower. I would still be curious how dry flower vaporizing would compare. Many methods of consumption burn plant matter or dissolve plant wax- this is bad. Only one method, dry flower convection vaporing, can get just the resin.

#11 | Posted by Brennnn at 2024-03-04 12:33 PM | Reply

Self-reported? Study is meaningless, as are all big-pharma funded anti-cannabis studies.

#12 | Posted by LegallyYourDead at 2024-03-04 12:43 PM | Reply | Newsworthy 1

"cannabis has a significant association with an increased risk of heart attack and stroke"

#10 | POSTED BY ONEIRONAUT

Based on another flawed survey as I clearly pointed out.

But, hey, it's sounds truthy so you go ahead and run with that like a good maga maroon do.

Maybe reschedule it as less dangerous as alcohol cigarettes and heroin and do a real scientific study and then get back to us.

But I won't hold my breath (unless I take a hit of some good old Jack Herer!).

#13 | Posted by donnerboy at 2024-03-04 01:31 PM | Reply | Newsworthy 2

And then he died.

#6 | POSTED BY DONNERBOY

How do you know Nulli is dead? I never heard this. Was there a notification?

#14 | Posted by Whatsleft at 2024-03-04 02:31 PM | Reply | Funny: 1

I think if this was truth or serious, we should have seen people falling out with these symptoms anywhere from 1968 on.

As a high school student during that time, there were MORE THAN AMPLE SUBJECTS that if this was a thing it certainly would have manifested itself by now.

#15 | Posted by fresno500 at 2024-03-04 02:59 PM | Reply

I miss Nullifidian. He was very interested in this issue and could debate the virtues of MJ use with anybody here.
#5 | POSTED BY EBERLY

I miss him too. He loved old-fashioned detective/mystery shows, and there are so many fantastic contemporary contributions to the genre these days on places like Brit Box and Acorn I'd love to tell him about.

#16 | Posted by Gal_Tuesday at 2024-03-04 03:13 PM | Reply

And then he died.

#6 | POSTED BY DONNERBOY

How do you know Nulli is dead? I never heard this. Was there a notification?
#14 | POSTED BY WHATSLEFT

Rcade told us. Like he told us about zatoichi's extinction, err, passing.

I can't remember if he told us how.

Was hoping someone else might remember that.

#17 | Posted by donnerboy at 2024-03-04 03:43 PM | Reply

Ps. Rip for today's 500.

#18 | Posted by fresno500 at 2024-03-04 04:11 PM | Reply

----. Haven't really been around here much the last few years. Work, and life, and a bit tired of toxic politics. Didn't know Nulli died. That's a gut punch.

On the subject of the thread, seems like that would need a lot more to prove it. Article lists a connection, but like most such things, does cannabis increase risk of cardiovascular damage, or are people who use cannabis more likely to take part in other activities that could also increase cardiovascular damage? Cannabinoids tend to be anti inflammatory. Just saw yet another article linking them to apoptosis in melanoma cells. I'd worry a lot more about drinking than an edible.

RIP Nulli. Hilarious, smart, often surprising with takes that could be everywhere from hard left to libertarian. Damn.

#19 | Posted by zeropointnrg at 2024-03-04 04:56 PM | Reply | Newsworthy 2

Nulli was a good dude. We grew up in the same area.

An old friend of mine was a daily toker. To hear his wife tell it, he was puffing in his garage with a couple friends and they were laughing like hell. All of a sudden, John dropped on the floor. They thought he was playing, but, it turns out he was in cardiac arrest and didn't make it to the hospital.

It sounds like an after school special, but it's the truth.

When I used to toke, I'd sometimes get heart palpitations. But, everybody is different. Smoke 'em if yer got 'em.

#20 | Posted by lee_the_agent at 2024-03-04 05:22 PM | Reply

@#17 | POSTED BY DONNERBOY

I'm pretty sure Boaz reported it , about 3 or 4 years ago.

#21 | Posted by shane at 2024-03-04 05:26 PM | Reply

I can understand smoking it. Cannabis smoke always felt more harsh than cigarettes, but Edibles?!? I find that odd.

#22 | Posted by shane at 2024-03-04 05:40 PM | Reply

I'm pretty sure Boaz reported it , about 3 or 4 years ago.

#21 | POSTED BY SHANE

Thanks. I thought it had come from Rcade. But yes it's been about 3-4 years. I was shocked by it then too. But now I realize it can happen to anyone anytime no matter which path you choose ... death is as close as your skin. We just try not to think about it all the time. And sometimes cannabis really helps with that!

But it's true that life is much more intense when you remember death is just a breath away.

Momento Mori.

#23 | Posted by donnerboy at 2024-03-04 07:27 PM | Reply | Newsworthy 1

Nulli was someone it was fun and educational to debate with; not many like him here today.

He and I were like Statler and Waldorf, though I don't remember who started that meme.

We always had Paris.... I mean, toking in Paris.

#24 | Posted by Corky at 2024-03-04 07:53 PM | Reply | Newsworthy 1

@#5 ... I miss Nullifidian. He was very interested in this issue and could debate the virtues of MJ use with anybody here. ...

... and climate change. He said his degree was in that field.

A great person to debate and discuss.

RIP Nullifidian.

#25 | Posted by LampLighter at 2024-03-04 08:00 PM | Reply

Is this "discovery" really new?

The electrophysiological effects of delta-9-tetrahydrocannabinol (cannabis) on cardiac conduction in man (1977)
www.sciencedirect.com

#26 | Posted by LampLighter at 2024-03-04 08:15 PM | Reply

Willie Nelson would like a word...

#27 | Posted by lfthndthrds at 2024-03-04 08:52 PM | Reply | Newsworthy 1

Sounds like more reefer madness garbage.

And... it's garbage. The claim that 17% of Americans have ever used cannabis is way below the 50% that Gallup found last year.

The claim that 90% haven't used it in the past year is also garbage, given that 17% consider themselves regular users according to more reputable surveys.

So... Funding. It's funded by the feds, specifically the NIH. No obvious ties to pharma for this study... but....

The authors... The lead author (Abra M. Jeffers) has been trying to find some connection for years. She tried in 2020 and failed with a Colorado study (https://www.ahajournals.org/doi/10.1161/circ.141.suppl_1.P250). Stanton Glantz is an anti-smoking activist. Salomeh Keyhani has been going after cannabis for years, was an author on a thoroughly ridiculous story about "cannabis use disorder". She has received big pharma money for a PTSD drug, which would face direct competition from cannabis. Amy L Byers has a few cannabis studies that would appear to be intended to be designed to be negative toward cannabis.

#28 | Posted by DarkVader at 2024-03-04 10:25 PM | Reply | Newsworthy 2

So... Funding. It's funded by the feds, specifically the NIH. No obvious ties to pharma for this study... but....

You'd be surprised to know how closely big pharma is tied into the research studies at NIH.

#29 | Posted by AMERICANUNITY at 2024-03-05 12:45 AM | Reply

@#28 ... reefer madness garbage ...

As a spoof movie, it is one of my favs.

Sadly, when it was released, it was not a spoof. It was thought to be real. (so many other topics come to mind at this point, but I'll try to stay focused...)

Much like Florida's State Surgeon General Joseph Ladapo appointment. Many thought it was a spoof. But, it turned out to be real. And now, Floridians are getting sick.

(OK, I lost it with that one... I'll keep trying...)


But, I digress, back to Reefer Madness...

Yeah, there is an anti-marijuana, I'll say, crowd among us.

But this connection to heart problems seems to have some legs to it.

So, at this point, I'm not yet ready to dismiss the concerns.

#30 | Posted by LampLighter at 2024-03-05 01:10 AM | Reply

Next up, we find out long term alcoholics have liver problems.

#31 | Posted by sitzkrieg at 2024-03-05 11:28 AM | Reply

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